Horseshoe
crabs are arthropods that live primarily in shallow ocean waters on soft sandy or muddy bottoms. They will, however, occasionally come on shore, e.g. for mating.
They are commonly used as bait and in fertilizer, and in recent years there has been a decline in number of individuals, as a consequence of coastal habitat destruction in Japan and overharvesting along the east coast of North America. Tetrodotoxin may be present in the roe of species inhabiting the waters of Thailand. Horseshoe crabs are considered living fossils.
Behind their legs, they have book gills, which exchange respiratory gases and are also occasionally used for swimming. While they can swim upside down, they usually are found on the ocean floor searching for worms and mollusks, which are their main food. They may also feed on crustaceans and even small fish.
The entire body of the horseshoe crab is protected by a hard shell. They have two large compound eyes and multiple smaller simple ones atop the carapace. Beneath the carapace they look quite similar to a large spider. They have five pairs of legs for walking, swimming and moving food into the mouth. The long, straight, rigid tails can be used to flip themselves over if they are turned upside down, so a horseshoe
crab with a broken tail is more susceptible to desiccation or predation.
Unlike humans, horseshoe crabs do not have hemoglobin in their blood, but instead use hemocyanin to carry oxygen. Because of the copper present in hemocyanin, their blood is blue. Their blood contains amebocytes, which play a role similar to white blood cells for vertebrates in defending the organism against pathogens. Amebocytes from the blood of L. polyphemus are used to make Limulus amebocyte lysate, which is used for the detection of bacterial endotoxins.